Liposomes are tiny, spherical vesicles (microscopic bubbles) made of one or more layers of phospholipids — the same kind of molecules that form the membranes of your body’s cells.

Key Features of Liposomes

1. Structure
– Outer shell: Made of phospholipids arranged in a bilayer (two layers back-to-back).
– Core: Contains water or water-soluble substances.
– Fat-loving interior of the bilayer: Can trap fat-soluble substances.

This means liposomes can carry both water-soluble and fat-soluble compounds at the same time.

2. Size

– Ranges from ~50 nanometers (nm) to several micrometers.
– Smaller sizes are often used for supplements and drug delivery because they can pass through biological barriers more easily.

3. Natural Compatibility

– Because they’re made from the same material as cell membranes, liposomes can fuse with cells and release their contents directly inside.

How They Work

  • The phospholipid bilayer acts as a protective bubble around whatever is inside.
  • In supplements or medicine, this protects delicate nutrients/drugs from being broken down in the stomach or by enzymes before they reach the bloodstream.
  • Once near target tissues, liposomes can merge with cell membranes, delivering their payload directly into the cell.

Why Liposomal Delivery Can Be a Game-Changer

  • For fragile nutrients: Vitamins like C, glutathione, or curcumin are notoriously difficult for the body to absorb in useful amounts. Liposomes help more of these compounds survive digestion and reach cells intact.
  • For people with digestive issues: If you have compromised gut function, liposomal delivery can bypass some absorption bottlenecks.
  • Lower doses, higher effect: Because more of the nutrient gets into your bloodstream, you may need less to achieve the same benefit.